Human Health Metabolism-Cancer, Obesity, and Diabetes

Oncogenomics

Cancer is basically an unhealthy tissue growth regulation. so as for a traditional cell to remodel into a neoplastic cell, the genes that regulate cell growth and differentiation should be altered. The affected genes square measure divided into 2 broad classes. Oncogenes square measure genes that promote cell growth and copy. Tumor suppressor genes square measure genes that inhibit cellular division and survival. Malignant transformation will occur through the formation of novel oncogenes, the inappropriate over-expression of traditional oncogenes, or by the under-expression or disabling of tumor suppressor genes. Typically, changes in multiple genes square measure needed to remodel a traditional cell into a neoplastic cell.